
2024
Sulconazole inhibits PD-1 expression in immune cells and cancer cells malignant phenotype through NF-κB and calcium activity repression. Pernot S, Tomé M, Galeano-Otero I, Evrard S, Badiola I, Delom F, Fessart D, Smani T, Siegfried G, Villoutreix BO, Khatib AM.Front Immunol. 2024 Jan 5;14:1278630. doi: 10.3389/fimmu.2023.1278630. eCollection 2023.PMID: 38250065
2023
OTX2 duplications: a recurrent cause of oculo-auriculo-vertebral spectrum. Celse T, Tingaud-Sequeira A, Dieterich K, Siegfried G, Lecaignec C, Bouneau L, Fannemel M, Salaun G, Laffargue F, Martinez G, Satre V, Vieville G, Bidart M, Soussi Zander C, Turesson AC, Splitt M, Reboul D, Chiesa J, Khau Van Kien P, Godin M, Gruchy N, Goel H, Palmer E, Demetriou K, Shalhoub C, Rooryck C, Coutton C.J Med Genet. 2023 Jun;60(6):620-626. doi: 10.1136/jmg-2022-108678. Epub 2022 Nov 11.PMID: 36368868
2023
Inhibition of the membrane repair protein annexin-A2 prevents tumor invasion and metastasis. Gounou C, Rouyer L, Siegfried G, Harté E, Bouvet F, d'Agata L, Darbo E, Lefeuvre M, Derieppe MA, Bouton L, Mélane M, Chapeau D, Martineau J, Prouzet-Mauleon V, Tan S, Souleyreau W, Saltel F, Argoul F, Khatib AM, Brisson AR, Iggo R, Bouter A.Cell Mol Life Sci. 2023 Dec 13;81(1):7. doi: 10.1007/s00018-023-05049-3.PMID: 38092984
2023
Annexin-A5 and annexin-A6 silencing prevents metastasis of breast cancer cells in zebrafish. Gounou C, Bouvet F, Liet B, Prouzet-Mauléon V, d'Agata L, Harté E, Argoul F, Siegfried G, Iggo R, Khatib AM, Bouter A.Biol Cell. 2023 Jun;115(6):e202200110. doi: 10.1111/boc.202200110. Epub 2023 Apr 7.PMID: 36958013
2022
Targeting PCSK9 in Liver Cancer Cells Triggers Metabolic Exhaustion and Cell Death by Ferroptosis. Alannan M, Fatrouni H, Trézéguet V, Dittrich-Domergue F, Moreau P, Siegfried G, Liet B, Khatib AM, Grosset CF, Badran B, Fayyad-Kazan H, Merched AJ.Cells. 2022 Dec 23;12(1):62. doi: 10.3390/cells12010062.PMID: 36611859
2010
Zebrafish ProVEGF-C expression, proteolytic processing and inhibitory effect of unprocessed ProVEGF-C during fin regeneration. Khatib AM, Lahlil R, Scamuffa N, Akimenko MA, Ernest S, Lomri A, Lalou C, Seidah NG, Villoutreix BO, Calvo F, Siegfried G.PLoS One. 2010 Jul 2;5(7):e11438. doi: 10.1371/journal.pone.0011438.
