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2024

Apela promotes blood vessel regeneration and remodeling in zebrafish. Nys N, Khatib AM, Siegfried G.Sci Rep. 2024 Feb 14;14(1):3718. doi: 10.1038/s41598-023-50677-1.PMID: 38355946

2024

Sulconazole inhibits PD-1 expression in immune cells and cancer cells malignant phenotype through NF-κB and calcium activity repression. Pernot S, Tomé M, Galeano-Otero I, Evrard S, Badiola I, Delom F, Fessart D, Smani T, Siegfried G, Villoutreix BO, Khatib AM.Front Immunol. 2024 Jan 5;14:1278630. doi: 10.3389/fimmu.2023.1278630. eCollection 2023.PMID: 38250065

2023

OTX2 duplications: a recurrent cause of oculo-auriculo-vertebral spectrum. Celse T, Tingaud-Sequeira A, Dieterich K, Siegfried G, Lecaignec C, Bouneau L, Fannemel M, Salaun G, Laffargue F, Martinez G, Satre V, Vieville G, Bidart M, Soussi Zander C, Turesson AC, Splitt M, Reboul D, Chiesa J, Khau Van Kien P, Godin M, Gruchy N, Goel H, Palmer E, Demetriou K, Shalhoub C, Rooryck C, Coutton C.J Med Genet. 2023 Jun;60(6):620-626. doi: 10.1136/jmg-2022-108678. Epub 2022 Nov 11.PMID: 36368868

2023

Inhibition of the membrane repair protein annexin-A2 prevents tumor invasion and metastasis. Gounou C, Rouyer L, Siegfried G, Harté E, Bouvet F, d'Agata L, Darbo E, Lefeuvre M, Derieppe MA, Bouton L, Mélane M, Chapeau D, Martineau J, Prouzet-Mauleon V, Tan S, Souleyreau W, Saltel F, Argoul F, Khatib AM, Brisson AR, Iggo R, Bouter A.Cell Mol Life Sci. 2023 Dec 13;81(1):7. doi: 10.1007/s00018-023-05049-3.PMID: 38092984

2023

Annexin-A5 and annexin-A6 silencing prevents metastasis of breast cancer cells in zebrafish. Gounou C, Bouvet F, Liet B, Prouzet-Mauléon V, d'Agata L, Harté E, Argoul F, Siegfried G, Iggo R, Khatib AM, Bouter A.Biol Cell. 2023 Jun;115(6):e202200110. doi: 10.1111/boc.202200110. Epub 2023 Apr 7.PMID: 36958013

2022

Targeting PCSK9 in Liver Cancer Cells Triggers Metabolic Exhaustion and Cell Death by Ferroptosis. Alannan M, Fatrouni H, Trézéguet V, Dittrich-Domergue F, Moreau P, Siegfried G, Liet B, Khatib AM, Grosset CF, Badran B, Fayyad-Kazan H, Merched AJ.Cells. 2022 Dec 23;12(1):62. doi: 10.3390/cells12010062.PMID: 36611859

2017

Regulation of the proprotein convertases expression and activity during regenerative angiogenesis: Role of hypoxia-inducible factor (HIF). Ma J, Evrard S, Badiola I, Siegfried G, Khatib AM.Eur J Cell Biol. 2017 Aug;96(5):457-468. doi: 10.1016/j.ejcb.2017.06.001.

2016

Integration of zebrafish fin regeneration genes with expression data of human tumors in silico uncovers potential novel melanoma markers. Hagedorn M, Siegfried G, Hooks KB, Khatib AM.Oncotarget. 2016 Nov 1;7(44):71567-71579.

2016

Biological outcome and mapping of total factor cascades in response to HIF induction during regenerative angiogenesis. Khatib AM, Lahlil R, Hagedorn M, Delomenie C, Christophe O, Denis C, Siegfried G.Oncotarget. 2016 Mar 15;7(11):12102-20. doi: 10.18632/oncotarget.7728.PMID: 26933814

2010

Zebrafish ProVEGF-C expression, proteolytic processing and inhibitory effect of unprocessed ProVEGF-C during fin regeneration. Khatib AM, Lahlil R, Scamuffa N, Akimenko MA, Ernest S, Lomri A, Lalou C, Seidah NG, Villoutreix BO, Calvo F, Siegfried G.PLoS One. 2010 Jul 2;5(7):e11438. doi: 10.1371/journal.pone.0011438.

Publications scientifiques

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